The combination of chemical diagnostics with microinstrumentation poses interesting challenges for fluid handling and delivery. At MISL a strong microfluidics program is underway to study fluidic dynamics and interface fluid handling with microelectromechanical instrumentation.


Substrate & Fluidic Interconnects

Modular Substrate and Fluidic Interconnects

Special MicroJoints are used to create reversible connections between tubing and microchannels within silicon and/or glass substrates and to bridge from microchannels within one substrate to another.

Fluidic "Quick" connects

Fluidic Quick connects

The "quick-connect" was fabricated in silicon and has fluidic channels and vias to direct the fluid as well as finger MicroJoints to integrate the "quick-connect" with other fluidic components and systems.

Fluidic I/O

Fluidic I/O

At MISL convenient fluidic I/O has been realized by micromachining silicon hexagonal microtubing to fit standard, commercial flexible tubing.

Fluidic Microsystems

Fluidic Microsystems

By combining available micromachining technologies, MISL is working to provide practical fluidic microsystems.

Fluidic MicroChannel Arrays

Fluidic MicroChannel Arrays

A first generation prototype of a modular, microfabricated separation and detection microsystem capable of parallel chemical separation and analysis of analytes is presented.

Micro-instrumentation for Endothelial Cell Research

Micro-instrumentation for Endothelial Cell Research

Endothelial cells (ECs) line the inner surfaces of arteries and affect the attachment of arteriosclerosis-causing plaque. Elongated ECs are resistant to plaque attachment, while rounded ECs are more prone to development of the disease. Therefore, there is a critical need for elucidating the potential role of shape in regulating EC function.

Microfluidic Interconnection Technology

Microfluidic Interconnection Technology

A new approach to realize silicon based microfluidic systems has been integrating mutli-level fluidic "circuit boards" with versatile geometries.